About 5 results found for searched term "E3 ligase Ligand 4" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9834 | E3 ligase Ligand 4 | Ligand for E3 Ligase |
| Thalidomide 4-fluoride | ||
| E3 ligase Ligand 4 (Thalidomide 4-fluoride) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it can connect to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1. | ||
| M9832 | E3 ligase Ligand 2 | Ligand for E3 Ligase |
| Thalidomide-4-OH; Cereblon ligand 2 | ||
| E3 ligase Ligand 2 (Thalidomide-4-OH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it can be connected to the ligand for protein by a linker to form PROTACs. | ||
| M9836 | Pomalidomide-PEG4-C-COOH | E3 Ligase Ligand-Linker Conjugates |
| E3 Ligase Ligand-Linker Conjugates 1 | ||
| Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker. | ||
| M14862 | (S,R,S)-AHPC-PEG4-NH2 hydrochloride | PROTAC |
| VH032-PEG4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 4 hydrochloride; E3 ligase Ligand-Linker Conjugates 7 | ||
| (S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. | ||
| M54696 | DGY-09-192 | PROTAC |
| DGY-09-192 is a bivalent degrader that couples the pan-FGFR inhibitor BGJ398 to the CRL2VHL E3 ligase-recruiting ligand, which induces degradation of FGFR1/2 and largely avoids degradation of FGFR3/4.DGY-09-192 exhibits a nanomolar DC50 against both wild-type FGFR2 and several FGFR2 fusions. In addition, DGY-09-192 has antiproliferative activity in gastric and cholangiocarcinoma cells. | ||
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